Arsene Wenger

Most appearances (all competitions)
Theo Walcott – 381
Patrick Vieira – 377
Thierry Henry – 371
Dennis Bergkamp – 350
Kolo Toure – 325

Most goals (all competitions)
Thierry Henry – 227
Robin van Persie – 131
Theo Walcott – 104
Olivier Giroud – 98
Dennis Bergkamp – 90

Eddie Howe

Appearances
Simon Francis – 211
Marc Pugh – 203
Steve Cook – 196
Harry Arter – 184
Brett Pitman – 177

Goals
Brett Pitman – 83
Marc Pugh – 38
Lewis Grabban – 34
Callum Wilson – 34
Matt Ritchie, Charlie Austin – 31

Chris Hughton

Appearances
David Stockdale – 116
Bruno – 111
Lewis Dunk – 103
Dale Stephens – 100
Tomer Hemed – 89

Goals
Tomer Hemed – 31
Andy Carroll – 28
Kevin Nolan – 25
Glenn Murray – 23
Anthony Knockaert – 20

Sean Dyche

Appearances
Sam Vokes – 183
Tom Heaton – 174
Scott Arfield – 173
Ben Mee – 170
David Jones – 131

Goals
Sam Vokes – 54
Danny Ings – 40
Andre Gray – 33
Scott Arfield – 20
Ashley Barnes – 14

Antonio Conte

Appearances
Leonardo Bonucci – 137
Gianluigi Buffon – 131
Andrea Pirlo – 120
Giorgio Chiellini – 118
Andrea Barzagli – 116

Goals
Arturo Vidal – 34
Barreto – 25
Diego Costa – 22
Carlos Tevez – 21
Mirko Vucinic – 21

Frank de Boer

Appearances
Ricardo van Rhijn – 165
Lasse Schone – 155
Siem de Jong – 139
Davy Klaassen – 138
Daley Blind – 136

Goals
Siem de Jong – 54
Arkadiusz Milik – 47
Lasse Schone – 36
Davy Klaassen – 36
Kolbeinn Sigthorsson – 35

Ronald Koeman

Appearances
Graziano Pelle – 159
Maxwell – 134
Jordy Clasie – 134
Victor Sikora – 116
Tomas Galasek – 113

Goals
Graziano Pelle – 87
Zlatan Ibrahimovic – 44
Rafael Van der Vaart – 40
Lex Immers – 27
Romelu Lukaku – 26

David Wagner

Appearances
Marc Hornschuh – 114
Zlatan Alomerovic – 111
Jonas Hofmann – 96
Tammo Harder – 79
Nakhi Wells – 78

Goals
Nakhi Wells – 24
Jonas Hofmann – 21
Tammo Harder – 21
Marvin Ducksch – 21
Terrence Boyd – 20

Craig Shakespeare

Appearances
Kasper Schmeichel – 16
Riyad Mahrez – 16
Jamie Vardy – 16
Christian Fuchs, Danny Simpson, Marc Albrighton, Wilfred Ndidi – 15

Goals
Jamie Vardy – 9
Marc Albrighton – 3
Riyad Mahrez – 3
Roberth Huth, Islam Slimani, Wilfred Ndidi – 2

Jurgen Klopp

Appearances
Neven Subotic – 281
Roman Weidenfeller – 279
Mats Hummels – 242
Kevin Grosskreutz – 235
Marcel Schmelzer – 232

Goals
Robert Lewandowski – 102
Michael Thurk – 56
Marco Reus – 53
Lucas Barrios – 49
Pierre-Emerick Aubameyang – 41

Pep Guardiola

Appearances
Lionel Messi – 219
Xavi – 208
Dani Alves – 208
Victor Valdes – 200
Sergio Busquets – 191

Goals
Lionel Messi – 211
Thomas Muller – 79
Robert Lewandowski – 67
Pedro – 58
Arjen Robben – 47

Jose Mourinho

Appearances
John Terry – 265
Ricardo Carvalho – 234
Frank Lampard – 213
Petr Cech – 195
Didier Drogba – 186

Goals
Cristiano Ronaldo – 168
Karim Benzema – 79
Didier Drogba – 73
Frank Lampard – 70
Gonzalo Higuain – 58

Rafael Benitez

Appearances
Jamie Carragher – 325
Pepe Reina – 303
Steven Gerrard – 292
Xabi Alonso – 210
Dirk Kuyt – 201

Goals
Steven Gerrard – 103
Fernando Torres – 87
Gonzalo Higuain – 53
Dirk Kuyt – 51
Mista – 49

Mauricio Pellegrino

Appearances
Leandro Desabato – 85
Guido Carrillo – 79
Gaston Gil Romero – 74
Carlos Auzqul – 73
Leonardo Jara – 69

Goals
Guido Carrillo – 29
Diego Vera – 16
Roberto Soldado – 11
Martin Benitez – 9
Edgar Mendez – 8

Mark Hughes

Appearances
Brad Friedel – 183
Brett Emerton – 160
Morten Gamst Pedersen – 156
Erik Pieters – 151
Marko Arnautovic – 145

Goals
Benni McCarthy – 35
Peter Crouch – 31
Morten Gamst Pedersen – 29
Jonathan Walters – 28
Craig Bellamy – 27

Paul Clement

Appearances
Johnny Russell – 33
Jason Shackell – 32
Chris Martin – 31
Richard Keogh – 31
Tom Ince, Cyrus Christie – 28

Goals
Fernando Llorente – 9
Chris Martin – 9
Tom Ince – 8
Jacob Butterfield – 6
Johnny Russell, Gylfi Sigurdsson – 4

Mauricio Pochettino

Appearances
Christian Eriksen – 143
Harry Kane – 139
Eric Dier – 135
Hugo Lloris – 133
Joan Verdu – 131

Goals
Harry Kane – 94
Christian Eriksen – 32
Dele Alli – 32
Heung-Min Son – 29
Dani Osvaldo – 24

Marco Silva

Appearances
Goncalo – 102
Vagner – 101
Evandro – 86
Diogo Amado – 83
Gerso – 76

Goals
Steven Vitoria – 23
Konstantinos Fortounis – 21
Luis Leal – 19
Lica – 18
Evandro – 17

Tony Pulis

Appearances
Ryan Shawcross – 241
Rory Delap – 208
Ricardo Fuller – 207
Glenn Whelan – 198
Andy Wilkinson – 178

Goals
Ricardo Fuller – 50
Jonathan Walters – 34
Kenwyne Jones – 26
Liam Lawrence – 24
Gifton Noel-Williams – 23

Slaven Bilic

Appearances
Vedran Corluka – 84
Mark Noble – 81
Olcay Sahan – 81
Gokhan Tore – 81
Cheikhou Kouyate – 78

Goals
Demba Ba – 27
Eduardo – 24
Michail Antonio – 18
Olcay Sahan – 17
Andy Carroll – 16

Massive thanks to transfermarkt for this.

Source: http://www.football365.com/news/every-current-premier-league-managers-most-used-players