Chelsea have opened up a 13-point lead over United and a ten-point lead over Spurs on their march to the top of the table.
But cautious Conte is taking nothing for granted and still thinks there are five or six different teams who could challenge his side for the championship.
Asked whether he thought United and Spurs were already out of the race, the Blues boss said: “No. Absolutely not. This league, every game is always open.
“This league, every game is always open”
Chelsea boss Antonio Conte
“In every game anything can happen. You must go with great concentration to be focused, because you can play against each team and you can lose.
“Until the end, six or seven teams can fight for the title.”
Chelsea, who welcome Eden Hazard back for tomorrow’s clash with Crystal Palace, can make it a club record 11 wins in a row in a single season with a victory.
But Conte reckons their winning run could actually make it harder for his side because opposition teams suddenly have nothing to lose against them.
He said: “Sure, when you arrive from 10 wins in a row, there is a great respect for you, no?
“But this situation is a good situation for the opponent because, now, when they are playing against you, they have nothing to lose.
“We are winning. Now the position is more difficult for us to continue this way than for our opponents. They haven’t got anything to lose when they’re playing against us.”